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The Mastermind is a strategic killer who combines speed, infection, and manipulation to dominate Survivors. His power, Virulent Bound, allows him to dash forward, seizing Survivors and infecting them with Uroboros. Infected Survivors suffer from hindered healing and movement, and if they collide with obstacles during a Bound, they become injured. Skilled Mastermind players use quick dashes to control the map, disrupt healing, and apply constant pressure, keeping Survivors on edge.